cGMP Manufacturing
Cell Banking
BioCina meticulously maintains cell banks to support development and cGMP manufacturing needs. Our cGMP facility contains a dedicated suite for cell banking, incubation, and transfer.
Clinical Manufacturing
BioCina has the experience and capabilities to meet your clinical manufacturing needs.
Commercial Manufacturing
BioCina is fully equipped for commercial manufacture in our regulatory approved, cGMP production facility.
cGMP Equipment & Technology:
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Upstream Fermentation
- 150-500 L working volume fermenter
- Sterilize-in-place and clean-in-place capabilities
- 200 L nutrient feeding tank
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Midstream Purification
- Two jacketed holding vessels (550 L and 900L)
- Continuous flow centrifuge
- High pressure homogenizer
- Portable CIP skid
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Downstream Purification
- 2,900L refold tank
- AKTA™ Isocratic AKTA™ Gradient Chromatography skids and columns
- UNIFLUX™ Tangential flow filtration system
- Single use mix tanks (100-500L)
