Messenger RNA Capabilities
BioCina offers end-to-end mRNA contract development and manufacturing services.
Unleashing the Potential of mRNA
Our expert team brings extensive technical experience in plasmid manufacturing, in-vitro transcription, purification, and LNP encapsulation of mRNA products. We also offer single site solutions for analytical method development, method validation, product characterisation packages and stability studies.
BioCina’s customised solutions are designed to meet our clients’ specific needs, from preclinical through commercial scale manufacturing, in our state-of-the-art GMP facility.
mRNA Process Development and Manufacturing Capability
BioCina’s process development team is equipped to develop end-to-end mRNA manufacturing processes up to 1 L IVT and 1 L LNP encapsulation scale. In our large-scale clinical and commercial mRNA manufacturing train, we are capable of manufacturing 0.5L – 10 L IVT to meet your bulk mRNA drug substance needs. Our in-house LNP capabilities and be utilised for the manufacture of non-sterile drug products.
Comprehensive Services for Your Every Need
Quality &
Regulatory
We produce mRNA drug substance of the highest quality standards, in full compliance with all global regulatory requirements.
Process
Development
BioCina’s expert Poly Nucleic Acid Products team is equipped to develop end-to-end mRNA manufacturing processes up to 1 L IVT and 1 L LNP encapsulation scale.
Analytical
Development
Robust and compliant test methods are developed to ensure the quality, safety and efficacy of all products manufactured at BioCina.
cGMP
Manufacturing
End-to-end cGMP manufacturing of LNP encapsulated mRNA, including cell line development and cGMP manufacture of template plasmid DNA.
Technology
Transfer
Our highly structured approach, including comprehensive gap analysis and robust risk mitigation, ensures reliable technology and process transfers.
Our Expertise On Demand
Thought Leadership & Resources
